Journal of Taiwan Fisheries Research
Melanogenesis Inhibition and UV-protective Effects of Oyster Shell Water Soluble Extract
- Date：2010-06-30
- Volume：18
- No：1
- Page：77-86
- Auther：Yi-Kuan Tsai et al.
In order to enable effective utilization of oyster shell, the aim of this study was evaluating the melanogenesis inhibition and the protective effect against ultraviolet (UV) A/B-exposed of oyster shell water soluble extract (OWE). In the melanogenesis inhibition test, it was found that 2, 4, 8 and 16 mg/ml OWE inhibited the activity for tyrosinase in a concentration-dependent manner, and OWE also reduced the production of melanin on B16 melanoma cell. In addition, OWE promoted proliferation of HaCaT keratinocyte cell. At the concentration of 8 and 16 mg/ml, OWE protected keratinocyte cell against UVA/UVB-exposed damage, and the cell survivability and cellular protein content all were significantly higher than negative group. However, OWE showed no repair function on UVA/B-exposed damage.
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