In this study, two experiments were conducted to investigate the tolerances of acute and chronic cold shock stress on pompano. The extreme tolerance of acute cold shock in pompano was 12ºC. In the chronic cold shock experiments, the temperature was reduced from 26 ºC to 14 ºC within three days and then maintained at 14 ºC. After 24 hours, the RBC number and hematocrit in the plasma were lower than the control set, and then increased after 48 hours. Hemoglobin increased with time and was higher than the control set after 72 hours. The concentrations of glucose, lactate, and cortisol in the plasma of the fish kept in the cold pond also revealed significantly differences to the control set.